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4.2 Genetic susceptibility and microbiota interaction The impact of genetic polymorphism on IBD is primarily mediated by gut microbiota, highlighting the significance of host genetic variations in disease progression

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The most common cardiovascular (CV) manifestations in patients with type 2 diabetes are heart failure (HF), stable angina, nonfatal myocardial infarction (MI), peripheral arterial disease and ischemic stroke [2,3,4] which accounts for 60% of their deaths [5]