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The equilibrium of circulating urate levels hinges on the interplay between production and excretion, a delicate balance orchestrated by urate transporter functions across various epithelial tissues and cell types

The supernatant fraction of the cell suspension was collected for immunoprecipitation experiments with FLAG-beads to isolate the FLAG-FBI-1/SP1 complex from PC-3 cells

Synergistic photothermal antimicrobial therapy using graphene oxide/polymer composite layer-by-layer thin films

As a replacement strategy, lithium orotate (LiO), reported to bind A less avidly than lithium carbonate, raised parenchymal Li, reduced A and phospho-tau, and improved synaptic/myelin markers and behavior at physiological Li levels in AD mice, though these salt-specific advantages and translational implications remain preclinical [2123]