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During consultation, we review your medical history, weight-loss goals, lifestyle, and previous attempts at weight management to determine whether treatment may be appropriate

10.3389/fnagi.2023.1116065 231 YeM.BiY

Mean body weight reduction reached approximately 24 percent at the highest dose tier a magnitude that, investigators have noted, exceeds the Phase 2 outcomes reported for dual GLP-1/GIP agonists at comparable trial durations (PMID 37366315)

[5] GHS-R1a receptors are expressed not only on pituitary somatotrophs but also in the hypothalamic arcuate nucleus, where they are co-localized with neurons involved in reproductive hormone regulation