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doi: 10.1016/j.schres.2023.11.015 17 MassraliAAdhyaDSrivastavaDPBaron-CohenSKotterMR

[PMC free article] [PubMed] [Google Scholar] 17.Mazo D.F., de Oliveira M.G., Pereira I.V., Cogliati B., Stefano J.T., de Souza G.F., Rabelo F., Lima F.R., Ferreira Alves V.A., Carrilho F.J., et al

However, about 10-15% of acetaminophen is metabolized by CYP2E1 into a toxic metabolite known as NAPQI (N-acetyl-p-benzoquinone imine).[ref] Detoxification with glutathione: NAPQI then needs to be neutralized with glutathione, which is catalyzed using the GST genes