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It is usually induced in animal models by immunization with antigens from the thyroid, such as thyroglobulin or thyroid peroxidase, which induce the production of autoantibodies that attack thyroid cells (Liu et al

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The Hepatic Encephalopathy Scoring Algorithm (HESA) [8] combines clinical and neuropsychological assessment as a means of improving the sensitivity of grading and has shown promise in clinical trials [9]