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Future Directions: Research is expanding beyond weight loss to evaluate CagriSema's effects on cardiometabolic complications (cardiovascular disease, NASH, sleep apnea, HFpEF), special populations (adolescents, diverse ethnic groups), and quality of life outcomes

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Large randomized trials like SELECT (2024) showed that semaglutide reduced cardiovascular events by 18% in overweight or obese adults, despite rare thrombotic cases

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Patients can observe mood swings due to hormonal imbalance, detoxification effects, or changes in energy levels but these mood changes are mild in nature

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