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In this context, PH20, I-BET151, and PXS-5153A may indirectly counteract thyroid-related fibrosis by degrading ECM, inhibiting profibrotic signaling, or reducing collagen crosslinking

Ramachandran, A

Pyocyanin induces the secretion of IL-23 to promote the differentiation and activation of Th17 cells, a subset of T-helper cells that play a key role in sustaining chronic inflammatory states (159)