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When the body cant properly absorb B12 from food or supplements, symptoms like fatigue, brain fog, and low mood can develop

Inhibiting NNMT Expression Lowering the expression of the NNMT enzyme isnt anything new under the sun, as it is well-connected to several disease states: NNMT is implicated in various disease conditions such as metabolic disorders, neurodegenerative diseases and cancer, and tissue NNMT expression or plasma levels of its product MNA have been proposed as biomarkers for these conditions Other chronic metabolic diseases that are linked to NNMT expression include: Insulin resistance & diabetes Heart disease Kidney disease Liver disease Parkinsons disease Chronic inflammation Im not suggesting that 5-Amino 1MQ will directly lead to reducing your risk of any of the diseases above that time will come when researchers finally smarten up and start testing the peptide in human clinical trials

Every fat-metabolism, NAD+, SIRT1 and lean-mass effect described above is preclinical (rodent or cell) only and should be read as a hypothesis, not an established human benefit

The mechanism is selective NNMT inhibition reducing adipocyte methyl-flux toward 1-methylnicotinamide