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doi: 10.1038/s41467-019-09865-9 28 ChengMShengLGaoQXiongQZhangHWuMet al

In this study, metabolic signatures were nearly identical between pre-ASD newborns and neurotypical newborns, and differential signatures were observed only in 5-year-olds, suggesting that ASD-associated metabolic signatures develop with age and the maturation of their respective gut microbiota [315]