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doi: 10.1016/j.ijgo.2007.10.024, PMID: [DOI] [PubMed] [Google Scholar] 32

This decline is associated with several aging signs and health issues, such as reduced muscle mass, increased body fat, decreased bone density, and slower recovery from injuries

This was the first comprehensive biopsy study proving bitter taste receptors exist throughout the human GI tract, providing the foundation for the bitter brake hypothesis