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Testosterone Therapy A 2025 pilot study (La Vignera et al., Reprod Biol Endocrinol ) followed 83 overweight men for 8 weeks: Group A: weekly tirzepatide (2.5 mg then 5 mg) Group B: transdermal TRT (AndroGel 1.62%) at manufacturer's guideline-based dosing Men in the tirzepatide group lost more weight and waist circumference and showed a natural rise in testosterone and a fall in estradiol
Central actions of the chemokine stromal cell-derived factor 1 contribute to neurohumoral excitation in heart failure rats
Psychiatry 208 , 108113 (2016)
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