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The occurrence of hepatic stellate cells can activate hepatic stellate cells and further induce their proliferation, synthesize a large amount of cell matrix, and deposit in the extracellular space, ultimately causing liver fibrosis [40, 41]

Rosuvastatin was not mutagenic or clastogenic with or without metabolic activation in the Ames test with Salmonella typhimurium and Escherichia coli, the mouse lymphoma assay, and the chromosomal aberration assay in Chinese hamster lung cells

Niacinamide (2%) helps stimulate collagen synthesis and improve the protective functions of the skin, helps reduce transepidermal loss of moisture from the skin and reduce pigmentation, softens, increases skin elasticity, moisturizes, tightens pores, soothes, brightens

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