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The mechanisms of iron-overload-induced bone loss mainly include the increased osteoclastogenesis and bone resorption capacity of osteoclasts [131], lipid peroxidation accumulation and ferroptosis in osteoblasts [132]
Due to lipid peroxidation, polyunsaturated fatty acids inhibiting the spermatozoa membrane are particularly sensitive to the penetration of free radicals
Wu Q, Rayman MP, Lv H, Schomburg L, Cui B, Gao C et al (2015) Low Population Selenium Status Is Associated With Increased Prevalence of Thyroid Disease