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Binvignat, M., Sellam, J., Berenbaum, F

According to NICE Technology Appraisal 875, Wegovy is recommended for use within the NHS for adults with a BMI of at least 35 kg/m and at least one weight-related comorbidity, or a BMI of at least 30 kg/m with type 2 diabetes, when provided through specialist weight management services

Both groups lost a similar amount of weight about 13% of body weight over 6 months

| Sustained weight maintenance data | Limited | Yes (STEP 5, 104 weeks) | Tesofensine produces faster weight loss on a per-month basis, while semaglutide produces greater total weight loss over a longer treatment period and has demonstrated sustained results with continued use