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Firstly, metformin inhibits mitochondrial complex 1, and this in turn may reduce the production of reactive oxygen species [85, 86], thought to be involved in cellular damage and mitochondrial dysfunction

La MAP se produit lorsque les vaisseaux sanguins rtrcis ne fournissent pas suffisamment de sang aux muscles lorsquils en ont besoin, le plus souvent aux muscles des jambes

BAP1 suppresses tumor development by inducing ferroptosis upon SLC7A11 repression