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In a recent study, Tan and coworkers engineered and expressed two GLP-1 analogues by genetically fusing a modified GLP-1 (Ala8Gly) to one or two tandem HSA-binding DARPins through a (GGGGS) 3 flexible linker

These studies lay a foundation for developing dual IGF-IR/InsR inhibitors such as BMS-754807 and linsitinib (OSI-906)

There's encouraging news as several FDA-approved medications harness similar scientific principles specifically for chronic weight management, such as Wegovy, Oral Wegovy, Zepbound, and Foundayo, which Klinic prescribes

In addition, this treatment is not intended for pregnant or breastfeeding women