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In addition to the systematic reviews in the literature (particularly the study by Italiner and colleagues), recent research has revealed promising findings regarding the circadian rhythms of components such as glucose, adiponectin, leptin, prolactin, zinc, sodium, 2-AG, potassium, copper, and iodine

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Semaglutide was dosed for the full period, while antibody dosing with the -MSTN and -ActA antibodies was started in Week 2 as an add-on to semaglutide and dosed through Week 12 (and was presumed to have more durable actions due to the extended half-life of the antibodies)