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Although enzymatic catalysis has been extensively explored in developing turn-on fluorescent probes, investigations into utilizing enzymatic reactions to regulate molecular aggregation states to realize more sophisticated and multifunctional biomedical applications remain rare 23,24,25

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Despite this promise, several critical limitations remain: No large-scale, randomized controlled human trials to confirm efficacy, safety, or long-term impact Toxicology and pharmacokinetic data are lacking, especially for chronic use or high-dose regimens Only one stereoisomer (all-L form) has been tested

(2) The scientists compared the potential of GHK-Cu to other peptides and vitamin C and vitamin A derivatives on photodamaged skin