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More importantly, serum levels of IL-1 and IL-18, two inflammatory injury biomarkers, were increased significantly in l-carnitine-fed female and male rats, disturbing liver function and injury

KG-dependent dioxygenases CRISPR library construction We constructed a pooled sgRNA library containing 64 sgRNAs targeting various genes whose enzymes require KG as a co-factor for their activity in addition to controls targeting intragenic regions as described previously (Joung et al., 2017) ( Table S1 )

The absence of mortality in rats after administering 105,000 mg/kg of methanolic leaf extract of J