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Formula-3 Wherein, 'Rf represents substituted or unsubstituted aryloxy and the substituents wherever necessary can be independently selected from halogens such as F, CI, Br & I, NO2 and the substitution can takes place at single or multiple positions on aryl group or Ri is In the second aspect of the second embodiment of the present invention, the conversion is carried out by deprotection of Lysine at position 20, coupling of compound of formula-3 to the backbone at Lysine followed by global deprotection and cleavage of the peptide chain from the Resin

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The preparation of semaglutide tablets and injection are described below: Semaglutide Tablets Tablet Semaglutide Preparation- Picture courtesy: bmi doctors The semaglutide tablet preparation is based on a series of steps involving with preparation of raw material, crushing, and sieving, followed by the granulation, drying, mixing, and ends with final compression