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hCiPSCs-Treated Group At the genus level, hCiPSCs treatment in the VPA-induced ASD model induced substantial shifts in gut microbiota composition (Figure S2C), with Bifidobacterium and Akkermansia exhibiting the most significant enrichment, accompanied by notable increases in Faecalibaculum and Christensenella

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Mechanistic insights indicated that this anticancer activity was mediated through the induction of apoptosissupported by elevated caspase-3 activity and an increased Bax/Bcl2 ratioas well as the activation of oxidative stress pathways 22