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Of note, the extent of the demonstrated beneficial effect on recovery of muscle function and integrity is considerable, and involves the transection- (15, 37) crush- (16, 17) lesion of striated muscle, and healing impairment induced by systemic corticosteroid application (16), as well as function impairment induced by centrally acting agents (74, 75)

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Doses are adjusted, therapy is paused, or discontinued entirely where indicated

Gene expression is calculated with the delta-delta Ct method (2 -Ct ) where the value of mRNA in the control, non-treated group is considered to be equal to 1