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Though this peptide structurally resembles GLP-1, and is encoded by proglucagon, crucially, it is resistant to DPP-4 mediated breakdown ( Figure 2 )

Common side effects of Wegovy include: Gastrointestinal symptoms : Nausea (affecting up to 44% of patients), vomiting, diarrhoea, constipation, and abdominal pain are the most frequently reported adverse effects

The most commonly reported side effects are gastrointestinal, including nausea, vomiting and diarrhoea these were reported by 74 per cent of participants in the Wegovy pill trial

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