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doi: 10.1007/s11916-020-00898-0

Vitamin B12 is a water-soluble vitamin, meaning that your body excretes what you dont need in your urine, including any excess consumed via supplements or food

Prioritize metformin where indicated, inositol, and peptides that improve insulin sensitivity

Since the liver is the major site of IGF-1 production, when steatosis develops lowering insulin sensitivity, the severity of steatosis at different stages of insulin resistance and metabolic syndrome seems to be correlated with worsened circulating IGF-1 levels [234]