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Tirzepatide Weight Loss Performance (SURMOUNT Trials) In the pivotal SURMOUNT-1 clinical trials, Tirzepatide was evaluated over 72 weeks in adults with obesity or overweight conditions without type 2 diabetes

Most trials followed participants for 68 to 176 weeks

This shift often leads to: Increased fat storage, particularly around the abdomen Slower metabolism Mood swings, poor sleep, and low energyall of which can make lifestyle changes more difficult By restoring hormonal balance, HRT can improve overall well-being and make weight loss more achievable

Other less common, but more serious, side effects include: pancreatitis, bowel obstruction, and gallstones