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Published evidence is narrower: topical skin and wound studies exist, hair claims are more indirect, and FDA materials caution that injectable GHK-Cu has limited human safety data [2], [3], [8]

This evidence secured FDA approval for weight-loss indication in 2021, yet insurance coverage remains sparse

discontinue if weight loss is less than 5% Regular weight measurements and BMI calculations Monitoring for adverse effects, particularly gastrointestinal symptoms Blood pressure and cardiovascular risk factor assessment Periodic blood tests to monitor metabolic parameters For patients with diabetes who are taking insulin or sulfonylureas, doses of these medications may need to be reduced when starting GLP-1 receptor agonists to prevent hypoglycaemia

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