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Future work will therefore focus on combining XChem hit matter with the main NMR hit series through structure-guided merging and linking of fragments to design more potent, drug-like, and cell-permeable tool compounds

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Bekiari, Apostolos Tsapas, Socioeconomic aspects of incretin-based therapy

Currently, the molecular switch that converts ferroptosis from protective to pathogenic remains undefined, requiring longitudinal studies to map temporal changes in ferroptosis regulators