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Pet insurance [can] mitigate costs, but pet owners expressed frustration over the high premiums and question whether insurance is worth the cost for aging pets (Theme 3: Pet insurance and budgeting in Section 3.5.4)

It resists breakdown by gastric acid, a property tied to the sequence itself

They're not proof something doesn't work they're a reason to keep expectations modest and timelines realistic

Current Evidence Level Stating the evidence tier precisely, without softening: Weighing the positive and negative studies The positive human evidence is real but structurally weak, and the weakness is specific: nearly all of it comes from a single investigator group