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The symmetry of results across left and right cheeks, forehead, and chin all within a narrow range reflects a systemic, whole-face effect consistent with an orally administered supplement acting through the bloodstream rather than a topically applied product

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Inhibition of KEAP1 by RTA 408 disinhibits the antioxidant transcription factor nrf2 and has neuroprotective and seizure reducing effects in the kainic model of TLE (Shekh-Ahmad et al., 2018)

Altered renal lipid metabolism and renal lipid accumulation in human diabetic nephropathy