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For storage beyond 28 days, aliquot the solution into small sterile vials and freeze at negative-20 degrees Celsius, which preserves potency for up to six months, though each freeze-thaw cycle degrades approximately 812% of the peptide

A dedicated phase 3 RENEW trial which investigates the efficacy and safety of the drug in patients with obesity or who were overweight, but without associated comorbidities is scheduled to start in late 2025.

Appetite and craving effects can appear within 1-2 weeks

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