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reported that gastrodin inhibits both the TLR4/TRAF6/NF-B pathway and Stat3 signaling, reducing microglial activation, pro-inflammatory responses, and neuronal damage in neurodegenerative diseases such as AD (Wang et al., 2024a)

[DOI] [PMC free article] [PubMed] [Google Scholar] 186.Abreu, A

[DOI] [Google Scholar] 107.Redha A.A., Perna S., Riva A., Petrangolini G., Peroni G., Nichetti M., Iannello G., Naso M., Faliva M.A., Rondanelli M

10.3390/ijms19030833 Summary Keywords post stroke depression, natural products, antidepressant, pathological mechanism, molecular mechanism Citation Gao H, Sai Y, Shang R, Zhong X, Kong L, Liu J and Wang K (2025) Post stroke depression: pathogenesis and molecular mechanisms of natural product-based interventions