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Nonviral retrograde gene transfer of human hepatocyte growth factor improves neuropathic pain-related phenomena in rats

Twice-daily dosing (500mcg morning and evening) shows up in more aggressive protocols but adds cost and injection logistics on top of an already-active TRT schedule

Sikiric et al., 2020b), this provides overcoming (Seiwerth et al., 2018) of the technical and practical limitations now presented as shortage in the corresponding standard angiogenic growth factors applicability and diverse delivery and carrier systems (see Practical Application as Support )