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Fourth, GLP-1R protein is more prevalent in axon terminals than in neuronal cell bodies, and it is possible that endogenous GLP-1 and GLP-1R agonists may bind to GLP-1 receptors in regions beyond those in which GLP-1R mRNA is expressed

Thus, glutamate-mediated, K + -associated excitatory activity may increase astrocytic energy demands as much as neuronal

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