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Makkar SR, Zhang SQ, Cranney J (2010) Behavioral and neural analysis of GABA in the acquisition, consolidation, reconsolidation, and extinction of fear memory

Given the role of acylcarnitine in maintaining the homeostasis of oxidative metabolism in mitochondria (17), our findings lend support to the existence of multiple intertwined biochemical mechanisms and pathways contributing to neurodegeneration and pain in DPN (42)

For example, not including inflammatory markers such as IL-1, IL-6, or C-reactive protein (CRP), markers of metabolic risk such as C-peptides or insulin resistance index, and oxidative stress markers such as plasma isoprostanes limited the interpretation of our findings to support the antioxidant compensation hypothesis, in particular in subjects with OWOB