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Healthcare providers should maintain open communication with patients about the theoretical thyroid risks while emphasizing the substantial metabolic benefits of tirzepatide and the absence of an established causal relationship to thyroid cancer in humans

About the review This review aims to simultaneously promote GLP-1 RA research and enhance users' understanding by synthesizing evidence from recent landmark trials, thereby providing a comprehensive picture of the potential of these drugs as more than just metabolic modulators

10.1017/S0029665120006916 186 MasuiR.SasakiM.FunakiY.OgasawaraN.MizunoM.IidaA.et al (2013)

Constipation or Diarrhea GI motility changes affect bowel habits