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This regulation helps prevent both buildup of damaged proteins and excessive proteolytic (protein breakdown)

Methylene blue is used to reduce oxidative stress, enhance mitochondrial respiration as an electron carrier, and promote the clearance of tau proteins (a group of proteins primarily found in the brain that play a critical role in maintaining the structure and function of neurons) and amyloid plaques (abnormal deposits of a protein called beta-amyloid (A) in the brain, a hallmark feature of Alzheimer's disease and other neurodegenerative conditions), which are implicated in diseases like Alzheimers, Parkinsons, and Huntingtons disease

10.1016/j.jaad.2010.11.061 8 AtaH.CemilB

In vivo, it has been observed that xenografts tumors are more resistant to FK866 treatment when NAPRT is upregulated, while they became more chemosensitive when NAPRT is silenced or inhibited