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Secondly, more investigations are needed to reveal the role of ferroptosis, especially when multiple pathological conditions coexist in DKD, and whether different factors affect each other

Novel glutathione-dependent thiopurine prodrugs: evidence for enhanced cytotoxicity in tumor cells and for decreased bone marrow toxicity in mice

Its activation of intracellular pathways like PI3K-AKT and MAPK, which are essential for cellular proliferation and differentiation, has also drawn the attention of scientists (6)

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