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Mol Metab 39:101008 Ravn P, Madhurantakam C, Kunze S, Matthews E, Priest C, OBrien S et al (2013) Structural and pharmacological characterization of novel potent and selective monoclonal antibody antagonists of glucose-dependent insulinotropic polypeptide receptor

As a GIP receptor agonist, tirzepatide enhances insulin secretion in a glucose-dependent manner, reduces glucagon secretion, and may improve insulin sensitivity

A 2025 Frontiers review of seizure reports identified 20 individuals described in case reports or case series after kratom use, but the authors concluded the evidence was not strong enough to prove kratom alone causes seizures because medical records were inconsistent and dose-response data were often missing

JSS is a member of the board of directors for Applied Therapeutics and Dexcom