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Lifestyle diets such as the Mediterranean diet and ketogenic diet can positively influence both motor and non-motor symptoms of patients with Parkinsons, reduce systemic inflammation, and increase dopamine-producing cells

Recent data from the ATTAIN-MAINTAIN trial showed that patients transitioning to orforglipron after injectable GLP-1 therapy maintained their weight loss with minimal regain (approximately 0.9 kg after semaglutide transition), suggesting that oral maintenance strategies could minimize the lean mass depletion seen with prolonged high-dose injectable therapy