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Tomin T, Bordag N, Zgner E, Al-Baghdadi A, Schinagl M, Birner-Gruenberger R, et al

Jiang S, Xu L, Chen Y, et al

A key concept for understanding this interface is that while health-damaging behaviors (e.g.: poor diet, excessive alcohol consumption, sleep deprivation and circadian disruption) contribute to allostatic load and the many consequences of such behaviors on triggering and exacerbating these illnesses, it is increasingly recognized that health-promoting behaviors that protect mitochondrial metabolism and energy regulation are an essential component of successful allostasis

Understanding whether these effects reverse after stopping treatment is crucial for informed decision-making