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The measurement of total homocysteine which includes the sum of the concentrations of free and bound homocysteine in the blood plasma, is technologically difficult

Its molecular formula is CHCuNO, and it has a molecular weight of approximately 403.9 Da

The dose of ebselen was chosen according to our published study (Figure 3, the protein expressions of GPX1 were significantly increased in peroxynitrite + ebselen group compared with the peroxynitrite-only group, while it was absent in the peroxynitrite + gpx1 / group (Figures 3AC)

However, brain zinc homeostasis is crucial because, while low levels are associated with neurological disorders such as Parkinsons disease or multiple sclerosis, high levels have been found in Alzheimers disease [127]