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Abbreviations AP: Acute Pancreatitis CP: Chronic pancreatitis SAP: Severe acute pancreatitis GC-MS: Gas chromatography-mass spectrometry AST: Aspartate Aminotransferase ALT: Alanine Aminotransferase GGT: Gamma-Glutamyl Transferase BUN: Blood Urea Nitrogen ALP: Alkaline Phosphatase CREA: Creatinine HE: Hematoxylin and Eosin ELISA: Enzyme-Linked Immunosorbent Assay HIF-1: Hypoxia-inducible factor 1 alpha VEGF: Vascular Endothelial Growth Factor PCoA: Principal Coordinates Analysis OPLS-DA: Orthogonal partial least squares discriminant analysis DEMs: Differential metabolites CI: Cerulein TNF-: Tumor Necrosis Factor-alpha IL-6: Interleukin 6 IL-1: Interleukin 1 beta MSP: Methylation-Specific PCR (Polymerase Chain Reaction) mTOR: Mammalian Target of Rapamycin p-mTOR: Phosphorylated Mammalian Target of Rapamycin NMDS: Non-metric Multidimensional Scaling References Lankisch PG, Apte M, Banks PA

doi: 10.1186/s12935-024-03391-5 [DOI] [PMC free article] [PubMed] [Google Scholar] 118

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