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Octreotide attenuates hepatic fibrosis and hepatic stellate cells proliferation and activation by inhibiting Wnt/-catenin signaling pathway, c-Myc and cyclin D1

KPV, the C-terminal tripeptide of -MSH (Lys-Pro-Val), has been investigated for its interaction with NF-B signaling, with researchers observing inhibition of NF-B nuclear translocation and downstream inflammatory cytokine expression (TNF-, IL-6, IL-8) in cell culture models