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Gastric sleeve surgery or sleeve gastrectomy, involves the removal of about 80% of the stomach, reducing its capacity and appetite hormones
Most insurance plans don't reimburse for medications purchased outside their approved pharmacy networks, especially compounded versions
Hence, while oral semaglutide and SGLT2 inhibitors offer comparable benefits for glycemic control and weight reduction, clinicians must consider the potential for skeletal muscle loss when prescribing SGLT2 inhibitors, particularly in those vulnerable to sarcopenia or frailty
While animal studies show promising results for tendon, muscle, and ligament repair, there are zero controlled human safety trials, and research suggests 12% to 58% of peptide products are contaminated, which is why the FDA classifies it as Category 2, and it's banned by WADA, NCAA, NFL, NBA, MLB, NHL, UFC, and PGA
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