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Although drinking of alcohol is considered a common social entertainment, male patients should be specifically warned of the negative effect of chronic alcohol consumption on the reproductive competence and advised to refrain from chronic alcohol consumption if they want to procreate and lead a normal sexual life

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reported that rosuvastatin alone or in combination with difluoromethylornithine significantly decreased polyamine content in the cells and increased intra-tumoral NK cells expressing perforin and IFN- when compared to untreated colon tumors [88]

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