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In our experiments, TEs-induced ferritinophagy in cardiomyocytes was characterized by elevated autophagy, increased ROS, and enhanced lipid peroxidation.The concept of ferritinophagy was introduced by Mancias et al

10.1002/epi4.12010 Epilepsia Open 67 ShahR.ShchepinovM

As we show here, the three catalytic sites of the complex are not perturbed due to oxidative modifications, retaining the ability to bind to the MV151 activity probe, suggesting that alterations in the gate conformation and/or the propagation of allosteric structural changes are those that impair the complex function

Vitamin B12 Boosts energy production, supports metabolism, and helps convert food into usable energy