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The ICV delivery was facilitated by surgically implanting a cannula connected to an Alzet micro-osmotic pump

Physiol Plant 100:255263 Noctor G, Gomez L, Vanacker H, Foyer CH (2002) Interactions between biosynthesis, compartmentation and transport in the control of glutathione homeostasis and signalling

Muscle contraction itself does it independently of insulin

Carriers of the UGT1A4*3 variant can experience reduced therapeutic efficacy due to ultrarapid glucuronidation, thus higher doses of some UGT1A4 substrates may be required for people carrying the UGT1A4*3 variant, such as seen during posaconazole treatment as an antifungal prophylaxis during treatment of hematological malignancies