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RELATED STORY | Pfizer moving forward with once-daily weight-loss pill seen as potential injection alternative Most of the reports showed the patients didn't know how to withdraw the medication from the vial into a syringe and inject themselves, per the agency

doi: 10.1038/s41598-021-89462-3 5 Al HassanM.EstrellesE.SorianoP.Lpez-GresaM

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CARDIOVASCULAR AND RENAL OUTCOMES TRIALS Because of concerns that diabetes drugs might lower glucose levels but lead to adverse cardiovascular outcomes, the FDA issued guidance for industry in 2008 requiring large long-term cardiovascular outcome trials of all new medications for treating type 2 diabetes (18)