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This means that a large portion of a traditional supplement may never actually reach the tissues where it is needed most

There were, however, no differences observed between the low or high dose luteolin treated groups and untreated mice regarding level of IgE, HDM-specific IgE, IgG, or IgG2a [162]

The excessive infiltration of SMs into synovia causes articular immune dysfunction, accelerates the progression of synovitis, and leads to osteoclast activation and ultimate bone erosion and joint destruction 7,8

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