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The clinical concern is not about drug testing but about gastroparesis risk: semaglutide slows gastric emptying, which can increase aspiration risk under general anesthesia if fasting protocols are not appropriately extended

Approval may take time and is not guaranteed

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Additionally, the FDA has documented specific safety concerns with compounded injectable semaglutide products, including reports of dosing errors related to dose-unit conversions that have led to overdosing